An outbreak of Escherichia coli O157 infection following exposure to a contaminated building

Publication Details

Authors: JK Varma, KD Greene, ME Reller, SM DeLong, et al.

Year: 2003

Source: JAMA

Publisher: jamanetwork.com

Citations: 258

Citations per Year: 11.73

Google Scholar Rank: 9

Author Count: 5

Abstract

Context: Infection with Escherichia coli O157 causes an estimated 70,000 diarrheal illnesses per year in the United States and can result in hemolytic-uremic syndrome and death. This outbreak investigation examines a unique case of E. coli O157 transmission following exposure to environmental contamination in a building, providing critical insights into non-foodborne transmission pathways and environmental persistence of this dangerous pathogen.

Key Findings

• First documented building-associated E. coli O157 outbreak
• Environmental contamination as transmission source
• Novel non-foodborne transmission pathway identified
• Clinical outcomes and case management strategies
• Environmental control and prevention measures

Research Impact

This landmark study (258 citations) published in JAMA demonstrated that E. coli O157 could be transmitted through environmental contamination in buildings, expanding understanding of transmission pathways beyond traditional foodborne routes and informing environmental health policies.

Publication Access

Full Text: JAMA

Full Article: Complete Article

Citation Information: Google Scholar Citations