HIV-associated TB in An Giang Province, Vietnam, 2001–2004: epidemiology and TB treatment outcomes

Publication Details

Authors: TT Thuy, NS Shah, MH Anh, DT Nghia, D Thom, T Linh, JK Varma, et al.

Year: 2007

Source: PLoS One

Publisher: journals.plos.org

Citations: 48

Citations per Year: 2.67

Google Scholar Rank: 66

Author Count: 7

Abstract

Background: Mortality is high in HIV-infected TB patients, but few studies from Southeast Asia have documented the benefits of interventions, such as co-trimoxazole (CTX), in reducing mortality and improving treatment outcomes. This comprehensive epidemiological study examines HIV-associated tuberculosis in An Giang Province, Vietnam, from 2001-2004, analyzing disease patterns, treatment outcomes, and the impact of specific interventions on patient survival. The research provides critical insights into TB-HIV co-infection management in rural Southeast Asian settings, documenting clinical outcomes, mortality factors, and the effectiveness of adjuvant therapies in improving survival rates among co-infected patients in resource-limited healthcare environments where dual infection poses significant challenges to patient management and public health control efforts.

Key Findings

• HIV-TB co-infection epidemiology and mortality patterns in rural Vietnam
• Co-trimoxazole prophylaxis effectiveness in reducing mortality and improving outcomes
• Treatment response patterns and clinical management strategies assessment
• Risk factor identification for poor outcomes in TB-HIV co-infected patients
• Evidence-based recommendations for adjuvant therapy and integrated care delivery

Research Impact

This important epidemiological study (48 citations) provided essential evidence on TB-HIV co-infection management in Southeast Asia, informing WHO guidelines and national TB programs by documenting benefits of co-trimoxazole prophylaxis and other interventions for improving survival outcomes in resource-limited settings.

Publication Access

Full Text: PLoS One

Citation Information: Google Scholar Citations